Sixth sense may refer to:

* Extrasensory perception (ESP), commonly called the sixth sense * Equilibrioception (sense of balance), the commonly accepted sixth physiological sense * In arts, media, and entertainment: ** The Sixth Sense (TV series) (The Sixth Sense (TV series)), a 1972 TV series on ABC starring Gary Collins and Catherine Ferrar ** The Sixth Sense, a 1999 film directed by M. Night Shyamalan ** Sixth Sense (mini-series), a weekly mini-series on British TV starring Cassandra Eason ** Sixth Sense Theatre Company, an amateur touring company based in Norfolk, UK ** "The 6th Sense", a song by the rapper Common