Siena College is an independent Roman Catholic liberal arts college in Loudonville (Loudonville, New York), in the town of Colonie (Colonie (town), New York), New York, United States. Siena is a four-year, coeducational, independent college in the Franciscan tradition, founded by the Franciscan Friars in 1937. It has 3,000 full-time students and offers undergraduate degrees in business, liberal arts, and sciences. Tuition for the 2009-2010 academic year total is $25,350 and standard room and board is $9,930.

It was named after Saint Bernardino of Siena, the illustrious 15th century Franciscan scholar and friar.