Darrin Horn (born December 24, 1972) is an American college basketball head coach. On April 1, 2008, Horn was hired as the new mens team coach at the University of South Carolina, replacing the retiring Dave Odom.

Horn played guard for the 1991 State Runner-Up Tates Creek Commodores in high school in Lexington, Kentucky. That fall he played for Western Kentucky University Hilltoppers in Bowling Green, Kentucky from 1991-1995. He was an assistant coach at Marquette University under Tom Crean (Tom Crean (basketball coach)) before he became the head coach at Western. Horn compiled a record of 111 wins and 48 losses in five seasons at his alma mater. He led the Hilltoppers to the "Sweet 16," the third round of the 2008 NCAA Mens Basketball Tournament. Their run ended with a 10-point loss to top-seeded UCLA.

Horns teams are known for their up-tempo style of play, full-court trapping defense, and conditioning. While at Western Kentucky, Horns teams averaged 47% field goal accuracy, and averaged about 77 points per game.

Horn is married to the former Carla Walker of Franklin, Tennessee. The couple has one daughter, Caroline, and one son, Walker.