Carlos Alberto Zambrano (born June 1, 1981, in Puerto Cabello, Venezuela), popularly known as "Big Z" or "El Toro", is a right-handed pitcher in Major League Baseball who has played for the Chicago Cubs since 2001 (2001 in baseball). He is signed with the Cubs until the 2012 season.

Zambrano, an imposing figure at 6 5" and 255 pounds, was signed by the Cubs as a free agent in 1997 and made his debut in 2001. After being used in both starting and relief (relief pitcher) duties, he enjoyed his first full season as a starter in 2003 (2003 in baseball), finishing with a 13-11 record, 168 strikeouts and a 3.11 ERA (earned run average).

Widely regarded as one of the best hitting pitchers in the game, Zambrano, a switch-hitter, has a career .236 batting average with 20 home runs, 58 RBIs (Run batted in) and a slugging percentage of .394. The 20 home runs are the most ever by a Cubs pitcher. He also tied with Ferguson Jenkins for the club record for home runs by a pitcher in a single season, hitting six in 2006. Due to his impressive stats at the plate he has been called on to pinch hit 19 times in his career and has won a Silver Slugger Award three times for his hitting.

Zambrano is one of only two National League pitchers to have won at least 13 games in each year from 2003-07, the other being former teammate Greg Maddux. In 2006, he became the first player from Venezuela to lead the National League in wins.