may refer to:

* Brothers & Sisters (2006 TV series) (Brothers & Sisters (2006 TV series)), an American television series * Brothers and Sisters (1979 TV series) (Brothers and Sisters (1979 TV series)), an American sitcom * "Brothers & Sisters" (song) (Brothers & Sisters (song)), a single by Coldplay * Brothers and Sisters (album) (Brothers and Sisters (album)), by The Allman Brothers Band * Brothers and Sisters, a novel by Ivy Compton-Burnett * The Brothers and Sisters (entertainment group) (1967-1972), a Robert Simpson production, once on the "Tonight" show. * In Christian liturgy, Brothers and Sisters is an opening line at the beginning of a sermon or homily.