Big Nothing is a 2006 British neo-noir comedy film directed by Jean-Baptiste Andrea starring David Schwimmer and Simon Pegg. It was released in December 2006, and had its premiere at Cardiff Film Festival (Cardiff) in November 2006.

Big Nothing was filmed on the Isle of Man and in Wales at Barry (Barry, Vale of Glamorgan) in the Vale of Glamorgan and at Caerwent and other areas of Monmouthshire. Other scenes were at Squamish, British Columbia, Canada.