Annie Duke (born Anne LaBarr Lederer; September 13, 1965) is a professional poker player and author who won a bracelet (WSOP bracelet) in the 2004 World Series of Poker $2,000 Omaha Hi-Low Split-8 or Better Event and was the winner of the 2004 World Series of Poker Tournament of Champions, where she earned the Winner-Take-All prize of $2,000,000.

In 2010 she won the National Heads-Up Poker Championship, earning a cash prize of $500,000 in addition to the title.